Publications

Original Papers 2024

  • Huang C, Seino J, Honda A, Fujihira H, Wu D, Okahara K, Kitazume S, Nakaya S, Kitajima K, Sato C, Suzuki T: Rat hepatocytes secrete free oligosaccharides. J. Biol. Chem. 300, 105712 (2024)
  • Hirayama H, Tachida Y, Fujinawa R, Matsuda Y, Murase T, Nishiuchi Y, Suzuki T: Development of a fluorescence and quencher-based FRET assay for detection of endogenous peptide:N-glycanase/NGLY1 activity. J. Biol. Chem. 300, 107121 (2024)
  • Li S-T, Hirayama H, Huang C, Matsuda T, Oka R, Yamasaki T, Kohda D, Suzuki T: Hydrolytic activity of yeast oligosaccharyltransferase is enhances when misfolded proteins accumulate in the endoplasmic reticulum. The FEBS Journal 291, 884-896 (2024)
  • Ueki M, Suzuki T, Kato Y: Large-scale cultivation of human iPS cells in bioreactor with reciprocal mixing. J. Biosci. Bioeng. 137, 149-155 (2024)
  • Sonoda Y, Fujita A, Torio M, Mukaino T, Sakata A, Matsukura M, Yonemoto K, Hatae K, Ichimiya Y, Chong PF, Ochiai M, Wada Y, Kadoya M, Okamoto N, Murakami Y, Suzuki T, Isobe N, Shigeto H, Matsumoto N, Sakai Y, Ohga S: Progressive myoclonic epilepsy as an expanding phehnotype of NGLY1-associated congenital deglycosylation disorder: A case report and review of the literature. Eur. J. Med. Genet. 67, 104895 (2024)
  • Fujihira H, Sato K, Nishiuchi Y, Murase T, Matsuda Y, Yoshida Y, Kamei T, Suzuki T: ELISA-based highly sensitive assay system for the detection of endogenous NGLY1 activity. Biochem. Biophys. Res. Commun. In press (https://doi.org/10.1016/j.bbrc.2024.149826)
  • S. Ito, and Y. Sugita*. “Free-energy landscapes of transmembrane homodimers by bias-exchange adaptively biased molecular dynamics”, Biophys. Chem. 307: 107190 (2024).
  • Chyzy, M. Kulik, A. Shinobu, S. Re, Y. Sugita, and J. Trylska*. “Molecular dynamics in multidimensional space explains how mutations affect the association path of neomycin to a riboswitch,” Proc. Natl. Acad. Sci. USA 121(15): e2317197121 (2024).
  • K. Watanabe, Q. Zhao, R. Iwatsuki, R. Fukui, W. Ren, Y. Sugita, and N. Nishida*. “Deciphering the multi-state conformational equilibrium of HDM2 in the regulation of p53 binding: Perspectives from molecular dynamics simulation and NMR analysis”, J. Am. Chem. Soc. 146, 9790-9800 (2024).
  • J. Jung, C. Tan, and Y. Sugita*. “GENESIS CGDYN: large-scale coarse-grained MD simulation with dynamic load balancing for heterogeneous biomolecular systems”, Nat Commun. 15, 3370 (2024).
  • Kuwashima Y, Yanagawa M, Maekawa M, Abe M, *Sako Y, *Arita M. TRPV4-dependent Ca2+ influx determines cholesterol dynamics at the plasma membrane. Biophys J 123, 1-18 (2024)
  • Hamamoto A, Kita N, Gowda SG, Takatsu H, Nakayama K, Arita M, Hui SP, *Shin HW. Lysosomal membrane integrity in fibroblasts derived from patients with Gaucher disease. Cell Struc Funct 49(1), 1-10 (2024)
  • Kita N, Hamamoto A, Gowda SG, Takatsu H, Nakayama K, Arita M, Hui SP, *Shin HW. Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis. J Lipid Res 65(3), 100508 (2024)
  • *Tsugawa H, Ishihara T, Ogasa K, Iwanami S, Hori A, Takahashi M, Yamada Y, Satoh-Takayama N, Ohno H, Minoda A, *Arita M. A lipidome landscape of aging in mice. Nature Aging in press